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产品材料

P904 – USPIO

 

P904 – USPIO

520.00 

Category: Preclinical MRI probes

Description

Catalogue Number P904
Description Ultra Small Particle of Iron Oxide (USPIO) for macrophage imaging
Main Applications Cellular imaging, inflammation imaging, angiography
Molecular characteristics
–  Hydrodynamic size: diameter is 25-30 nm
–  Fe content : > 5000 Fe atoms per particle
–  Recommended dose: 200 μmol/kg = 2.5 μL/g

Example: for a 30g body weight mouse injection, volume is 75 μL

 

–  Relaxivities ( s-1.mM-1, 37°C; 4% Human Albumin Serum, medium closed to plasma)
Bo(T)

1.5北京赛车pk10代理

3.0

4.7

7.0

r1

北京赛车pk10代理 14

7

4

1.6

r2

北京赛车pk10代理 90

90

92

北京赛车pk10代理 94

–  Qualitative techniques: Perl’s staining
–  In vitro quantification techniques: P904 is a Fe-based contrast agent. Thus, it is necessary to take into account the endoge- nous iron content for quantification in biological media by ICP- AES or ICP-MS. Another way for USPIO quantification is rela- xometry, which is poorly sensitive to endogenous iron content.
Characteristics of the vial –  Concentration: [Fe] = 4.47 mgFe/L

北京赛车pk10代理 –  Volume: 450 μL (5 mice dose approx.)

–  Other animal species: contact us

Storage Need to be stored at 4°C in a closed vial away from light
Notes For in vitro or animal use only
Selected publications [1] Corot et al, ed. Molecular and Cellular MR Imaging: CRC Press, 2007 [2] Kinner et al, Invest Radiol, 2011 [3] Kinner et al, Invest Radiol 2012 [4] Sigovan et al, Radiology 2009 [5] Raynaud et al, ISMRM 2010 [6] Lopez Castro et al, Nanoscale 2011 [7] T

Product Identification
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